Ultraviolet Shadowing of RNA Can Cause Significant Chemical Damage in Seconds
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منابع مشابه
Ultraviolet Shadowing of RNA Can Cause Significant Chemical Damage in Seconds
Chemical purity of RNA samples is important for high-precision studies of RNA folding and catalytic behavior, but photodamage accrued during ultraviolet (UV) shadowing steps of sample preparation can reduce this purity. Here, we report the quantitation of UV-induced damage by using reverse transcription and single-nucleotide-resolution capillary electrophoresis. We found photolesions in a dozen...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2012
ISSN: 2045-2322
DOI: 10.1038/srep00517